Product Description
Product Name |
Vonoprazan fumarate |
CAS No. |
1260141-27-2 |
Molecular Formula |
C21H20FN3O6S |
Molecular Weight |
461.4634032 |
Grade Standard |
Medicine Grade |
Purity |
99% min |
Vonoprazan fumarate is indicated for the treatment of gastric ulcer, duodenal ulcer and reflux esophagitis. Vonoprazan fumarate has a novel mechanism of action called potassium-competitive acid blockers, which competitively inhibit the binding of potassium ions to H+, K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells.
Function of Vonoprazan
Vonoprazan does not inhibit Na+, K+-ATPase activity even at concentrations 500 times higher than that of their IC50 values against gastric H+, K+-ATPase activity. Furthermore, the drug is unaffected by the gastric secretory state, unlike PPIs. .
Application of Vonoprazan
Treatment of duodenal ulcer, gastric ulcer and reflux esophagitis, gastric or recurrent duodenal ulcer caused by low-dose aspirin. Helicobacter pylori eradication, adjuvant treatment of the following diseases: gastric ulcer, duodenal ulcer, gastric MALT lymphoma, idiopathic thrombocytopenic purpura, early gastric cancer, Helicobacter pylori-infected gastritis..
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1.Package: 1kg/bottle or bag
25kgs/drum or bag
2.shipment: within 5 days after payment done
Shipping by Fedex ,DHL ,EMS or TNT