Apixaban CAS 503612-47-3 High Purity API Raw Material

• CAS No.: 503612-47-3
• Formula: C25h25n5o4
• EINECS: 639-684-6
• Model NO.: 503612-47-3
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: High Purity
• Colour: White
• Custom Clearence: 100% Safe Custom Clearence
• Lead Time: 1-3 Days
• Express Time: 3-7 Days
• Payment Method: T/T, Western Union, L/C, etc.
• Transport Package: Packed by Aluminum Foil Bag or Cardbaord Drum
• Specification: 99.9% Purity White Powder
• Trademark: Harvest
• Origin: Wuhan, Hubei, China
• Production Capacity: 50000kg/Year

Product Description

Product Description

Product Name	Apixaban
CAS No.	503612-47-3
Molecular Formula	C25H25N5O4
Molecular Weight	459.5
Grade Standard	Medicine Grade
Purity	99% min

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What is Apixaban?

Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with theconcentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.

Function and Application 

A key component in helping our customers be first to market is a responsive supply chain. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity. A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.

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1.Package:   1kg/bottle or bag

                      25kgs/drum or bag

 

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