Product Description
Product Name |
Apixaban |
CAS No. |
503612-47-3 |
Molecular Formula |
C25H25N5O4 |
Molecular Weight |
459.5 |
Grade Standard |
Medicine Grade |
Purity |
99% min |
.
What is Apixaban?
Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with theconcentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays.
Function and Application
A key component in helping our customers be first to market is a responsive supply chain. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity. A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.
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Packaging & Shipping
1.Package: 1kg/bottle or bag
25kgs/drum or bag
2.shipment: within 5 days after payment done
Shipping by Fedex ,DHL ,EMS or TNT