CAS No.: | 603-50-9 |
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Formula: | C22h19no4 |
EINECS: | 210-044-4 |
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Product Name | Bisacodyl |
CAS No. | 603-50-9 |
Molecular Formula | C22H19NO4 |
Molecular Weight | 361.39 |
Grade Standard | Medicine Grade |
Purity | 99% min |
Description:
Bisacodyl is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Bisacodyl is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movemen Bisacodyl is a stimulant laxative. It stimulates the muscles in the wall of the small intestine and colon to generate a bowel movement. It also alters water and electrolyte levels inintestines, increasing the level of fluids which also produce a laxative-like effect.
Application:
It is a safe and effective drug for the treatment of constipation.
1.stomach cramps
2.faintness
3.stomach discomfort
Function:
Properties: In common with other stimulant laxatives, bisacodyl (which is of a related structure to phenolphthalein) stimulates accumulation of water and electrolytes in the colonic lumen and enhances intestinal motility. It may stimulate sodium/potassium-ATPase which may account for a portion of its laxative activity. It may also increase the synthesis of prostaglandins and cyclic-AMP, and this may contribute to increased secretion of water and electrolytes. Bisacodyl is rapidly converted by intestinal and bacterial enzymes to its desacetyl metabolite. As much as 5% of an oral dose is absorbed and excreted in the urine as the glucuronide. This inactive metabolite is also excreted in the bile and may be hydrolyzed to active drug in the colon.
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