| CAS No.: | 668270-12-0 |
|---|---|
| Formula: | C25h28n8o2 |
| EINECS: | 1308068-626-2 |
|
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| Product Name | Linagliptin |
| CAS No. | 668270-12-0 |
| Molecular Formula | C25H28N8O2 |
| Molecular Weight | 472.54 |
| Grade Standard | Medicine Grade |
| Purity | 99% min |
1. Incretin (Incretin) has the role of intestinal promoting in sulin B cells to secrete in sulin, mainly including glucose-dependent in sulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). DDP-4 is a serine protease located on the cell surface, which is widely found in plasma and in vivo tissues (such as kidney, liver, small intestine villi, endothelial cells, etc.). Rilalitine is a selective DPP-4 inhibitor that inhibits the activity of the enzyme by reversibly binding to DPP-4, delays GLP-1 degradation, enhances GLP-1 activity, and stimulates glucose-dependent In sulin secretion, and reduce circulating levels of glucagon, thereby regulating blood glucose levels in patients with type 2 diabetes.
2. Compared with other DPP-4 inhibitors, the main advantages of liradetine is: with excellent renal safety, and can effectively reduce glycosylated hemoglobin. Lilardine mainly in the form of excretion of fecal excretion, the oral administration, the amount of renal excretion is only 5% of the dose, even if the intravenous administration, and only 30.8% of the excretion by the kidney, so the patient did not need treatment Regularly check the liver, kidney function and dose adjustment, all patients can be a unified fixed dose, easy to prescribe.
1.Package: 1kg/bottle or bag
25kgs/drum or bag
2.shipment: within 5 days after payment done
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